This seems to be the problem with DNA sequencing: too much data!
BGI, based in China, is the world’s largest genomics research institute, with 167 DNA sequencers producing the equivalent of 2,000 human genomes a day.
BGI churns out so much data that it often cannot transmit its results to clients or collaborators over the Internet or other communications lines because that would take weeks. Instead, it sends computer disks containing the data, via FedEx.
“It sounds like an analog solution in a digital age,” conceded Sifei He, the head of cloud computing for BGI, formerly known as the Beijing Genomics Institute. But for now, he said, there is no better way.
The field of genomics is caught in a data deluge. DNA sequencing is becoming faster and cheaper at a pace far outstripping Moore’s law, which describes the rate at which computing gets faster and cheaper.
The result is that the ability to determine DNA sequences is starting to outrun the ability of researchers to store, transmit and especially to analyze the data.
“Data handling is now the bottleneck,” said David Haussler, director of the center for biomolecular science and engineering at the University of California, Santa Cruz. “It costs more to analyze a genome than to sequence a genome.”
Though, one plus of this data deluge is that tech companies are learning how to handle vast quantities of data, something that bodes well for algorithm-based litigation assistance:
But the data challenges are also creating opportunities. There is demand for people trained in bioinformatics, the convergence of biology and computing. Numerous bioinformatics companies, like SoftGenetics, DNAStar, DNAnexus and NextBio, have sprung up to offer software and services to help analyze the data. EMC, a maker of data storage equipment, has found life sciences a fertile market for products that handle large amounts of information. BGI is starting a journal, GigaScience, to publish data-heavy life science papers.
If only Google would solve this problem:
Google might help as well.
“Google has enough capacity to do all of genomics in a day,” said Dr. Schatz of Cold Spring Harbor, who is trying to apply Google’s techniques to genomics data. Prodded by Senator Charles E. Schumer, Democrat of New York, Google is exploring cooperation with Cold Spring Harbor.
Google’s venture capital arm recently invested in DNAnexus, a bioinformatics company. DNAnexus and Google plan to host their own copy of the federal sequence archive that had once looked as if it might be closed.